Metabolic Disease Models

Diet-Induced NASH (Nonalcoholic Steatohepatitis) in Mice

Common Bile Duct Ligation Model (CBD) and Hepatic Duct Ligation Model (CHD)

Common Bile Duct Ligation Model (CBD) and Hepatic Duct Ligation Model (CHD)

Common Bile Duct Ligation Model (CBD) and Hepatic Duct Ligation Model (CHD)

Common Bile Duct Ligation Model (CBD) and Hepatic Duct Ligation Model (CHD)

Common Bile Duct Ligation Model (CBD) and Hepatic Duct Ligation Model (CHD)

For more information about our Metabolic Disease Models please

Common Bile Duct Ligation Model (CBD) and Hepatic Duct Ligation Model (CHD)

For more information about our Metabolic Disease Models please

Diet-Induced NASH in Mice

The model is a fast start, low cost model that will allow researches to examine drug effect in this most extreme form of NAFLD.


  • Body weight
  • Liver weight / body weight ratio
  • Liver morphological analysis
  • Clinical pathology
  • Fibrosis-related gene expression level
  • Histopathology analysis
  • Magnetic Resonance Imaging

Histopathology analysis

Histopathology analysis

Common Bile (CBD) and Hepatic Duct Ligation Model (CHD)

 

Bile duct ligation in rat

  • Body weight
  • Organ weight (liver, kidney, spleen)
  • Liver necropsy
  • Full hematology panel
  • Serum biochemistry
  • Histopathology for necrosis or fibrosis inflammation

image62